Diablo 4 Duriel: How to Farm the Summoning Materials and Kill Him

Lair Bosses stopped taking summoning materials with patch 2.2.0. You walk up to Duriel’s altar, and the fight starts.

The item you farm now is the Greater Lair Key. It opens his Hoard once he dies. Each player in the group spends a key of their own.

Step	What it takes
Start the fight	Nothing, the altar is free
Open his Hoard	1 Greater Lair Key
Get the key	Kill an Initiate Lair Boss
Difficulty	Torment 1 and up

Shard of Agony is his Boss Trophy today, a reward from the kill.

Need a stack of runs? A Pro can farm the resources for them on your account.

Greater Lair Keys come from a loop through the Initiate bosses.

1. Collect Lair Keys. Helltide, Tree of Whispers caches and War Plan activities all drop them.
2. Kill an Initiate Lair Boss. Varshan, Grigoire, the Beast in the Ice, Lord Zir and Urivar are the Initiate tier.
3. Open the Initiate Hoard with 1 Lair Key. The Hoard pays out a Greater Lair Key along with its loot.
4. Turn a Stygian Stone into a key. Initiates can also drop a Stygian Stone. It converts into any Greater key 1 for 1.

Every Lair Boss kill also gives Belial a chance to ambush you. Our Belial guide shows what that fight pays.

His lair is the Gaping Crevasse in southern Kehjistan, east of Gea Kul. The altar sits at the end of the dungeon.

• Claw combo. He slashes several times and ends with a ground stab that leaves a poison pool. Hit him from behind.
• Poison projectiles. His shots leave pools that stay on the ground. Keep a clean lane to fall back into.
• Grab and charge. A frontal grab and a long charge both punish whoever stands in front of him.
• Burrow phase. He digs underground and calls 2 elite minions. He comes back with poison maggots. Stay clear of the holes.

Most of his damage is poison. Raise your poison resistance before the run.

Duriel’s Hoard rolls from his own Unique table, with items for every class.

• Melted Heart of Selig. This amulet is his Iconic Mythic Unique. Our Selig guide covers its power.
• Smoldering Brimstone. He can drop this mount.

Belial can roll Duriel’s table too, with better Mythic odds. The Mythic Uniques guide lists the other bosses and their items.

Duriel moved into the Greater tier of Lair Bosses with patch 2.2.0 on 29 April 2025. That patch also removed the summoning cost.

Season 15 started on 15 September 2026 with patch 3.2.1. His Hoard still takes a Greater Lair Key. A later patch, 3.2.4, landed on 28 October 2026.

A Pro farms the resources for your Duriel runs on your character.

• Pack count. Pick how many resource packs you want on the page.
• Piloted or self-play. A Pro plays your character, or you play along.
• Seasonal or Eternal. Both realms work, for a Softcore or a Hardcore character.
• Duriel kills. Want the kills too? They have their own card above.

Tell the chat how many runs you plan.